Fuzzy's niece is killed in a stagecoach hold-up. Billy and Fuzzy quickly learn that the culprit, who not only killed all the passengers but also absconded with $40,000, may be holed up in lawless Pecos City.

Gallant Cisco "kidnaps" murder suspect Ellen from the authorities, then sets about to prove her innocence, all with the cooperation of a sympathetic sheriff.

After her stagecoach is ambushed, a woman is tasked with holding a dangerous outlaw captive and must survive the day when the bandit’s gang tries to free him.

A young woman finds a trunk full of stolen diamonds, takes them and heads westward, pursued by the thief.

Town banker John Martin calls on Billy and Fuzzy for help in capturing the men that robbed his bank.

Columbia's 11th serial and the first western serial that James W. Horne solo-directed.

A band of outlaws, led by "Papa" Clellan, hold up in a ghost town as they plan an attack on a wagon train loaded with gold. The unexpected arrival of a stagecoach forces the gang to hold the passengers and driver as hostages. The later arrival of a wanderer, John Trey, sets in motion events not in "Papa" Clellan's original plan.

Stage line owner Brent has his men robbing Halliday stages and when his manager Waring learns of it, Brent has him killed. Jeff Waring arrives and takes his uncle's job. He soon learns what's happening and the Durango Kid goes into action. This keeps Halliday going and gives them a chance to get the mail contract by winning the stagecoach race.

Jack Manning (Tim McCoy) arrives in a midwestern town from Gold Creek in Califonia. He brings a message from Goerge Woods (Francis Ford) to his brother Tom Woods (Francis Ford), in a dual role, and niece Mary (Allene Ray, informing them he has struck gold and asking them to join him in California via a wagon train. Jack and Mary fall in love to the great displeasure of Rance Carter (Wilbur McGaugh) who has a yen for Mary himself. Jack and Mary not only have to be wary of Carter's crooked ways and machinations, but also of Indian uprisings, caused by Carter.

Bandit Cheyenne Harry reforms because of the faith placed in him by Molly Young and her father. Soon, however, Harry is lured from the straight and narrow when he meets his old friend Ben Kent and consents to participate in Kent's plan of robbing a stagecoach.

In order to obtain a stage coach mail contract, a new road must be built. A gang of outlaws try to prevent the building of the road.

When Pegleg and his Black Raiders threaten the westward expansion of the United States, the government sends Kit Carson and David Brent to straighten things out.

In 1865, Captain Mark Smith of the Confederate Army leads a band of deserters to conquer Texas and rule it as a dictator. In one of his first actions, he captures and assumes the identity of Texas' new Finance Commissioner, Colonel Marcus Jeffries, after having the real man murdered. When a contingent of Texas Rangers enters the territory, Snead, one of Smith's men, leads them into an ambush by Smith's "troopers". The Rangers are apparently wiped out, although one injured survivor is left. The survivor, nursed back to health by Tonto, swears to avenge the massacre and defeat "Colonel Jeffries" and his men.

Sergeant MacLane of the Mounties investigates the disruptive activities of a bunch of troublemakers.

The Phantom Rider helps Mary Grayson thwart a plot to steal her land.

A new town doctor arrives at the same time as local Indians needprotection from troublemaking looters.

Government agents work to interfere with schemes to trick the Comanches into war with the Texans.

Kit Cardigan seeks the killer of his father...among other plot threads leading up to the famous historical incident.

Jesse James wants to start a new life in a new location, but quickly finds himself wrapped-up in protecting townsfolk from the machinations of evil oilmen.

Beyond Hell's Gate Pass is territory controlled by a man who calls himself King Carter; he uses a variety of schemes to prevent the railroad from being built, for fear it will finish his control of (what he considers) his land.