UFC 80: Rapid Fire was a mixed martial arts (MMA) event held by the Ultimate Fighting Championship (UFC), that took place on January 19, 2008 at the Metro Radio Arena in Newcastle, England. Sean Sherk was originally slated to fight but tested positive for steroids. With the lightweight championship vacated, the Penn-Stevenson bout was altered to be for the undisputed championship.

UFC 79: Nemesis was a mixed martial arts (MMA) event held by the Ultimate Fighting Championship (UFC), that took place on December 29, 2007 at the Mandalay Bay Events Center in Las Vegas, Nevada. The main event featured the highly anticipated rubber match between former UFC Welterweight Champions Georges St. Pierre and Matt Hughes. The Co-main event featured a fight between Chuck Liddell and Wanderlei Silva.

UFC 78: Validation was a mixed martial arts event held by the Ultimate Fighting Championship (UFC), that took place on November 17, 2007 at the Prudential Center in Newark, New Jersey. Validation was the first UFC event held in New Jersey since June 4, 2005's UFC 53: Heavy Hitters in Atlantic City. The main event featured TUF 2 Heavyweight winner Rashad Evans against TUF 3 Light Heavyweight winner Michael Bisping in a light heavyweight contest.

UFC 76: Knockout was a mixed martial arts (MMA) event held by the Ultimate Fighting Championship (UFC). The event took place on September 22, 2007 at the Honda Center in Anaheim, California. Though the event was subtitled Knockout, the entire card ironically produced no knockouts. The main event featured a fight between former Light Heavyweight Champion Chuck Liddell and The Ultimate Fighter 2 alum Keith Jardine, with both fighters returning from knockout losses at UFC 71.

UFC 75: Champion vs. Champion was a mixed martial arts (MMA) event held by the Ultimate Fighting Championship (UFC). The event was held September 8, 2007 at The O2 in London, England. The main event was a title unification match between UFC Light Heavyweight Champion Quinton Jackson and PRIDE Fighting Championships' 83 kg and 93 kg champion, Dan Henderson.

UFC 74: Respect was a mixed martial arts (MMA) event held by the Ultimate Fighting Championship (UFC). The event took place on August 25, 2007 at the Mandalay Bay Events Center in Las Vegas, Nevada. The main event was a UFC heavyweight championship bout which featured UFC heavyweight champion Randy Couture defending his title against Gabriel Gonzaga.

UFC 73: Stacked was a mixed martial arts (MMA) event held by the Ultimate Fighting Championship (UFC). It took place on July 7, 2007 at the ARCO Arena in Sacramento, California and featured a total of nine bouts: four on the preliminary card and five on the main card. The main event was Anderson Silva defending the UFC Middleweight Championship against Nathan Marquardt.

UFC 72: Victory was a mixed martial arts event held by the Ultimate Fighting Championship. The event took place Saturday, June 16, 2007 at The Odyssey in Belfast, Northern Ireland. Martin Kampmann was scheduled to fight Rich Franklin, but was forced to withdraw due to injury. Yushin Okami replaced Kampmann in the main event.

UFC 71: Liddell vs. Jackson was a mixed martial arts event held by the Ultimate Fighting Championship. The event took place on Saturday, May 26, 2007 at the MGM Grand Garden Arena in Las Vegas, Nevada. The main event was the rematch between UFC Light Heavyweight Champion "The Iceman" Chuck Liddell and Quinton "Rampage" Jackson. Jackson was the only fighter to have an unavenged win against Liddell.

UFC 70 was the second UFC event held in the United Kingdom, and the first in Manchester. The first UFC event in the UK was UFC 38: Brawl at the Hall on July 13, 2002. UFC 70 was also only the seventh UFC event held outside the United States, and the first since UFC 38. 2006 PRIDE Open-Weight Grand Prix Champion, Mirko Cro Cop fought Heavyweight contender Gabriel Gonzaga in the main event to determine the top contender for the UFC Heavyweight Championship held by Randy Couture.

UFC 69: Shootout was a mixed martial arts event held by the Ultimate Fighting Championship on Saturday, April 7, 2007 at the Toyota Center in Houston, Texas. The card was headlined by heavy favourite Georges St. Pierre defending his welterweight title against The Ultimate Fighter 4 welterweight winner Matt Serra.

UFC 68: The Uprising was a mixed martial arts event held by the Ultimate Fighting Championship on March 3, 2007 at the Nationwide Arena in Columbus, Ohio. In the main event, UFC Heavyweight Champion Tim Sylvia was set to defend his title against Randy Couture, who was coming out of a 12-month retirement. Couture, a former UFC Heavyweight and Light Heavyweight Champion, hadn't fought as a heavyweight since UFC 39 in 2002.

UFC 66: Liddell vs. Ortiz was a mixed martial arts event held by the Ultimate Fighting Championship on December 30, 2006. UFC 66's main event was a championship fight with two of the UFC's biggest light heavyweight stars, Light Heavyweight Champion Chuck Liddell defending his title against former champion Tito Ortiz.

UFC 65: Bad Intentions was a mixed martial arts competition held by the Ultimate Fighting Championship on November 18, 2006 at the ARCO Arena in Sacramento, California. The card featured the anticipated rematch between Matt Hughes and Georges St. Pierre for the UFC Welterweight Championship.

UFC 63: Hughes vs. Penn was a mixed martial arts event held by the Ultimate Fighting Championship on September 23, 2006. The event, originally subtitled "Hughes vs. St. Pierre," was scheduled to feature a UFC Welterweight Title match between champion Matt Hughes and Georges St.-Pierre. Nevertheless, a groin injury—which was reported early in August—forced St.-Pierre off the card.

UFC 89: Bisping vs. Leben was a mixed martial arts event held by the Ultimate Fighting Championship (UFC) on October 18, 2008 at the National Indoor Arena in Birmingham, England. The event was headlined by a middleweight bout between Michael Bisping and Chris Leben.

UFC 62: Liddell vs. Sobral was a mixed martial arts event held by the Ultimate Fighting Championship on August 26, 2006. The main event was a Light Heavyweight Title fight between Chuck 'The Iceman' Liddell and Renato 'Babalu' Sobral and the co-main event was a TUF finale re-match between Forrest Griffin and the 'American Psycho' Stephan Bonnar.

UFC 61: Bitter Rivals was a mixed martial arts event held by the Ultimate Fighting Championship on Saturday, July 8, 2006. The main event was a Heavyweight Championship match between champion Tim Sylvia and former champion Andrei Arlovski. The co-main event was the highly anticipated re-match of TUF 3 coaches Tito Ortiz and Ken Shamrock.

UFC 60: Hughes vs. Gracie was a mixed martial arts event held by the Ultimate Fighting Championship on May 27, 2006. Headlining the card was a non-title catch-weight (175 lb) match between Matt Hughes, former UFC Welterweight Champion, and Royce Gracie, the champion of UFC 1, UFC 2 and UFC 4. This was Gracie's first match in the UFC and in the United States since UFC 5.

UFC 59: Reality Check was a mixed martial arts event held by the Ultimate Fighting Championship on April 15, 2006 at Arrowhead Pond, in Anaheim, California, and broadcast live on pay-per-view in the United States and Canada. This was the first-ever UFC event held in California after the state's legalization of mixed martial arts contests.