To the Least of My Brothers and Sisters is a new documentary on the life of Jerome Lejeune, the Father of Modern Genetics that was made to celebrate the 20th anniversary of his death. Filmed on two continents, it contains numerous interviews with former colleagues, families, current medical researchers, and others, all who express the importance of Jerome Lejeune in both the history of medicine and the defense of the dignity of human life.

Could dyslexia be a gift? Or can it only ever be a disability? Documentary maker Richard Macer sets off on a road trip with his dyslexic son Arthur to find the answer. En route, they meet Richard Branson and Eddie Izzard, and many other successful dyslexic people. - BBC

Documentary about the making of ’Spring Break Zombie Massacre.’

The fourth film in a long series about Martina Schaub, a woman with Down's Syndrome. Tom Alandh documented part of her life from age 5 to 50. In this film, she is in her early twenties.

This documentary follows a small number of British people with an incurable genetic disease called Prader-Willi syndrome. This rare disorder makes the sufferer unable to control their eating habits. Prader–Willi syndrome is a rare genetic disorder in which seven genes (or some subset thereof) on chromosome 15 (q 11-13) are deleted or unexpressed (chromosome 15q partial deletion) on the paternal chromosome. The film is set in Gretton House, near Kettering in England, which is a government-funded care home deliberately constructed to assist people with PWS. The film focuses on a new resident, Joe Blackburn, who is 21 and begins the documentary weighing over 30 stone (190 kg, 420 lbs) and with fears for his health. Resident Tamara Allwood is also featured, who was at one point close to death from overeating.

A documentary about young people with autism, and how arts and creative therapies help them to lead fuller lives.

jefftowne is a 1998 documentary shot and directed by Daniel Kraus and distributed by Troma Entertainment. It chronicles the life of Jeff Towne, a 40 year old Iowa City resident who suffers from Downs Syndrome, obesity, alcoholism, and circulation problems. Towne also enjoys pornography and lives with his 90-year-old adoptive grandmother.

On the heels of a tragedy and the COVID-19 pandemic, a Dallas-based theatre troupe comprised of people with intellectual and developmental disabilities are determined to write, rehearse, and perform their 11th annual original musical.

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This documentary gives a look without prejudice into Down syndrome, exposing families and individuals with Down syndrome. Parents discloses their experiences from the moment the doctors tell them that their babies have Down syndrome and how they supersede their initial rejection by the feeling of the motherhood and parenthood. But the most important, the director and writer shows how the patients with Down syndrome may succeed in their lives, dancing, practicing sports, reading and even loving and getting married.

A group of friends with Down Syndrome have been attending the same school for 40 years, and they are tired of being treated like children, they are grown-ups and want to live as such.

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This one-of-a-kind comedy special showcases the comedian's riotous stand-up performance, exploring everything from the Disability experience to her Italian-Catholic upbringing to body image issues and more.

Entrepreneur Collette Divitto, who has Down syndrome, transforms workplace culture through her successful cookie company. Addressing the 83% unemployment rate among disabled people, she builds an inclusive business model built on individual strengths rather than perceived deficits. The film follows Collette's unique approach to hiring and workplace culture, showcasing the ripple effects of her leadership throughout the business community.

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Rob Krikke (33) has Down’s syndrome and is an actor with a theatre company. Since his sister died in an accident, that event won’t let go of Rob anymore. A decision is taken to make a play about her death. Documentary maker Didderiëns follows this process closely, shunning neither poetry nor confrontation.

The sporting journey of Team Santos, three athletes from Brighton Table Tennis Club, as they prepare to represent Great Britain at the European Down's Syndrome Championships.

MINDS Perform is a performing arts group consisting of members with learning disabilities. As they rehearse for a new song, they are transported into a kaleidoscopic world of music and dance. Commissioned for the Movement for the Intellectually Disabled of Singapore.

Documentary about the enigmatic and experimental music group "Reynols", his lead singer and leader who was down syndrome and the peculiarity of having a discography published in the most dissimilar corners of the planet.

Documentary about the obstacles handicapped people face when looking for love